Table 4

Percentage of patients within each imputed NAT2 phenotype with specified pathological characteristics of adenomatous polyps: the Minnesota Cancer Prevention Research Unit Polyp Study

Polyp characteristicsImputed NAT2 phenotype
Fast (n = 32)Intermediate (n = 196)Slow (n = 299)Total (n = 527)
No. of adenomas
 165.665.872.969.8
 2–334.429.621.725.4
 ≥40.04.65.44.7
Size of largest adenoma (cm)
 ≤0.550.049.550.850.3
 0.6–0.921.915.816.116.3
 ≥1.028.134.733.133.4
Subtype: most severe adenoma
 Tubular71.968.962.265.3
 Villous28.125.032.429.4
 Tubulo-villous0.06.14.74.9
Dysplasia: most severe adenoma
 None to mild53.146.939.843.3
 Moderate34.444.452.848.6
 Severe/carcinoma in situ12.58.77.48.2
Shape: most severe adenoma
 Pedunculated18.822.425.824.1
 Sessile43.854.650.551.6
Location: most severe adenoma
 Colon90.683.284.084.1
  Proximala9.415.818.116.7
  Distala81.267.465.967.4
 Rectuma9.416.816.015.9
  • a Proximal colon = cecum to hepatic flexure; distal colon = transverse colon to sigmoid; rectum includes rectosigmoid.