Table 2

Distribution of GSTM1 genotype by lung cases and controls and odds of lung cancer for the GSTM1 null genotype, ATBC Study, Finnish men

GSTM1 present n (%)GSTM1 null n (%)OR (95% CI)a
Control (n = 333)171 (51.4)162 (48.6)
Casesb
 Total (n = 319)159 (49.8)160 (50.2)1.09 (0.79–1.50)
  Squamous (n = 147)78 (53.1)69 (46.9)0.95 (0.63–1.42)
  Small cell (n = 47)22 (46.8)25 (53.2)1.19 (0.66–2.17)
  Adenocarcinoma (n = 55)29 (54.6)24 (45.4)1.00 (0.55–1.80)
  Other (n = 57)c30 (43.9)42 (56.1)1.41 (0.80–2.49)
  • a OR and 95% CI for the GSTM1 null versus GSTM1 present genotype adjusted for baseline age, years of smoking, daily cigarettes smoked, and intervention assignment.

  • b Thirteen cases could not be classified histologically and were not included in the analysis.

  • c Other subtypes include carcinoma, metastatic (n = 5), large cell (n = 7), undifferentiated (n = 26), anaplastic (n = 9), giant cell (n = 1), and not otherwise specified (n = 9).