Table 4

NAT2, GSTM1, and colon cancer risk: ORs and 95% CIsa

Imputed phenotypeMenWomen
No. (%)OR (95% CI)No. (%)OR (95% CI)
CasesControlsCasesControls
NAT1
 Slow536 (58.8)603 (58.2)1.0394 (55.3)553 (59.7)1.0
 Intermediate323 (35.4)361 (34.8)1.0 (0.8–1.2)281 (39.5)322 (34.7)1.2 (1.0–1.5)
 Fast53 (5.8)72 (7.0)0.9 (0.6–1.2)37 (5.2)52 (5.6)1.0 (0.7–1.6)
 Intermediate or fast376 (41.2)433 (41.8)1.0 (0.8–1.2)318 (44.7)374 (40.3)1.2 (1.0–1.5)
GSTM1
 Present436 (49.3)499 (49.1)1.0323 (47.9)386 (44.2)1.0
 Null448 (50.7)518 (50.9)1.0 (0.8–1.2)360 (52.1)486 (55.8)0.9 (0.7–1.0)
  • a Adjusted for age, BMI, calories, dietary fiber, lifetime physical activity, and usual no. of cigarettes smoked.