Table 2.

Characteristics of ovarian cancer cases and matched controls; NYUWHS, ORDET, and NSHDS

CharacteristicsCases (N = 230)Controls (N = 432)
Age at blood sampling, y, median (10th, 90th)54 (40, 64)55 (40, 64)
Time to diagnosis, y, median (10th, 90th)6.3 (1.3, 13.9)
Age at menarche, y, median (10th, 90th)13 (11, 15)13 (11, 15)
Unknown, n2429
Body mass index, kg/m2, median (10th, 90th)24.6 (20.4, 30.1)25.0 (21.0, 31.1)
Unknown, n1522
Menopausal status at baseline, n (%)
Premenopausal83 (36.2)157 (36.4)
Postmenopausal146 (63.8)274 (63.6)
Unknown11
Family history of breast or ovarian cancer, n (%)
No125 (77.6)270 (84.9)
Yes36 (23.4)48 (15.1)
Unknown b69114
Parity, n (%)
Nulliparous45 (22.5)70 (17.5)
Parous155 (77.5)331 (82.5)
Unknown3031
Age at first pregnancy, y, median (10th, 90th) a25 (21, 31)25 (20, 33)
Unknown, n56121
Use of OCs, n (%)
Never139 (69.8)237 (64.4)
Ever60 (30.2)131 (35.6)
Unknown3164
Use of hormone replacement therapy, n (%) c
Never123 (65.4)269 (75.4)
Ever65 (34.6)88 (24.6)
Unknown4275
Smoking status at baseline, n (%)
Former or never163 (74.4)303 (78.2)
Current56 (25.6)84 (21.8)
Unknown1145
Use of NSAIDs at baseline, n (%)
No167 (88.8)312 (89.1)
Yes21 (11.2)38 (10.9)
Unknown b4282
Use of vitamins at baseline, n (%)
No126 (67.0)228 (65.3)
Yes62 (32.0)121 (34.7)
Unknown b4283
Histology, n (%)
Serous120 (52.2)
Endometriod30 (13.0)
Clear cell16 (7.0)
Mucinous22 (10.0)
Undifferentiated8 (3.5)
Not otherwise specified21 (9.1)
Unknown13 (5.7)
  • aAmong everparous women.

  • bHigh frequency of missing because variable is not available from the ORDET cohort (41 cases and 82 controls).

  • cCases and controls were significantly different with regard to ever use of hormone replacement therapy (P = 0.02).