Table 4.

Physical function, fitness, and anthropometric outcomes at baseline, end point, and 6-month follow-up in the lifestyle intervention and usual care groups

Mean (SD)Group mean difference in Δa (95% CI)Adjusted PbMean (SD)Group mean difference in Δa (95% CI)Adjusted Pc
BaselineEnd point6-mo follow-up
Usual careInterventionUsual careInterventionUsual careIntervention
Fitness and function
 Exercise tolerance, s368.6 (129.1)351.1 (110.8)379.8 (129.2)495.8 (125.0)133.4 (92.4–174.4)<0.001351.0 (114.4)435.8 (118.5)102.2 (56.8–147.6)< 0.001
 Chair-sit-to-stand (reps)12.3 (3.7)11.1 (2.3)13.4 (4.3)16.0 (3.7)3.79 (1.68–5.90)0.00213.6 (3.8)16.1 (4.1)3.66 (1.71–5.60)0.001
 MVT, Nm170.8 (52.0)181.9 (42.7)169.2 (48.8)190.3 (40.9)9.97 (−0.92 to 20.8)0.033176.2 (53.8)195.5 (43.6)8.20 (−0.90 to 17.3)0.035
Anthropometry
 Weight, kg82.2 (8.1)83.1 (10.9)82.0 (8.1)82.2 (10.4)−0.72 (−1.8 to 0.35)0.2081.5 (8.2)81.8 (10.2)−0.64 (−2.2 to 0.87)0.27
 BMI, kg/m227.4 (2.7)28.0 (3.2)27.0 (3.2)27.6 (3.0)0.09 (−0.85 to 1.01)0.7627.3 (2.7)27.6 (3.1)−0.23 (−0.67 to 0.22)0.88
 Waist-to-hip ratio0.96 (0.07)0.96 (0.05)0.95 (0.06)0.96 (0.05)0.01 (−0.01 to 0.03)0.390.95 (0.05)0.95 (0.05)0.001 (−0.02 to 0.02)0.56

NOTE: Because 95% CI in the previous column is calculated on unadjusted data, the P value, which is adjusted for baseline score, will not necessarily be consistent with the CI.

aΔ (delta) from baseline in intervention group minus Δ from baseline in usual care group. A negative score indicates a greater decrease in the intervention group and a positive score a greater increase.

bP value for effect of group from an ANCOVA of end point score adjusting for baseline score.

cP value for effect of group from an ANCOVA of end point and 6-month follow-up scores adjusting for baseline score.