Table 1.

Incidence rates of CRC (1987–2006) adjusted for age, gender, race, and center in relation to selected characteristics at visit 1, ARIC studya

Characteristic at visit 1 (1987–1989)CRC cases (n = 308)PYIncidence rate per 1,000 PYs (95% CI)
Ageb
 45–494766,4890.69 (0.52–0.92)
 50–548562,1021.34 (1.08–1.66)
 55–598954,8861.60 (1.29–1.97)
 60–648747,0331.83 (1.48–2.26)
Genderc
 Male160128,4281.48 (1.26–1.74)
 Female148102,0801.09 (0.92–1.29)
Raced
 African American9258,6111.58 (1.29–1.94)
 Caucasian216171,8971.17 (1.01–1.34)
BMI, kg/m2
 ≤24.998475,9431.11 (0.89–1.37)
 25–29.9911991,9491.17 (0.97–1.41)
 ≥3010562,3371.57 (1.29–1.92)
Diabetes
 No26223,5491.21 (1.15–1.28)
 Yes4620,9051.64 (1.44–1.88)
Aspirin
 No173122,8991.29 (1.20–1.39)
 Yes131105,6681.21 (1.12–1.31)
Education
 <High school8550,8011.36 (1.07–1.72)
 High school9775,4231.30 (1.06–1.59)
 >High school126103,9441.18 (0.99–1.41)
Smoking
 Never13399,8171.18 (0.99–1.41)
 Former9875,1361.30 (1.06–1.59)
 Current7755,4221.36 (1.07–1.72)
Alcohol
 Never7758,3361.18 (0.92–1.52)
 Former5641,3201.18 (0.90–1.55)
 Current173129,8611.31 (0.11–1.53)
HRT (in women)
 Never9981,9481.15 (1.06–1.26)
 Ever4841,9471.10 (0.99–1.23)

Abbreviation: PY, person-year.

  • aTotal number of participants = 13,414.

  • bAdjusted for race, gender, and center.

  • cAdjusted for age (continuous), race, and center.

  • dAdjusted for age (continuous) and gender.