Table 2.

Multivariate-adjusted hazard ratios of all-cause death among colon cancer patients across anthropometric measures

Baseline anthropometric measureAll-cause HR (95% CI)
No. of all deathsAdjusted for age at diagnosisMultivariate-adjusted (1)*Multivariate-adjusted (2)Multivariate-adjusted (3)
Weight (pounds)
    ≤1391571 (reference)1 (reference)1 (reference)1 (reference)
    140-1651571.03 (0.83-1.28)1.13 (0.90-1.42)1.12 (0.89-1.42)1.13 (0.89-1.42)
    ≥1661791.29 (1.04-1.60)1.39 (1.10-1.76)1.37 (1.08-1.73)1.34 (1.07-1.69)
    P trend0.020.0050.0090.01
BMI (kg/m2)
    <18.5113.01 (1.63-5.57)1.89 (1.01-3.53)1.90 (1.01-3.57)2.01 (1.07-3.80)
    18.5-24.91451 (reference)1 (reference)1 (reference)1 (reference)
    25-29.91781.11 (0.89-1.38)1.12 (0.89-1.41)1.11 (0.88-1.40)1.11 (0.88-1.39)
    ≥301591.52 (1.22-1.91)1.45 (1.14-1.85)1.42 (1.11-1.82)1.46 (1.15-1.86)
WHR tertiles
    <0.811421 (reference)1 (reference)1 (reference)1 (reference)
    0.81-0.881601.31 (1.05-1.64)1.21 (0.96-1.53)1.20 (0.95-1.52)1.24 (0.98-1.57)
    >0.881871.51 (1.22-1.88)1.36 (1.08-1.72)1.34 (1.08-1.69)1.34 (1.06-1.69)
    P trend0.00020.0080.020.01
Waist tertiles
    ≤32.41431 (reference)1 (reference)1 (reference)1 (reference)
    32.5-37.41501.07 (0.85-1.34)1.11 (0.87-1.41)1.11 (0.87-1.41)1.10 (0.87-1.40)
    ≥37.51971.60 (1.29-1.99)1.45 (1.15-1.82)1.40 (1.13-1.81)1.41 (1.12-1.77)
    P trend0<0.00010.0010.0030.003
  • *(1) Adjusted for age at diagnosis, stage, education, and smoking (smoking status and number of pack-years).

  • (2) Analysis (1) adjusted for history of heart disease and diabetes as time-dependent covariates.

  • (3) Analysis (1) adjusted for first course treatment surgery, chemotherapy, and radiation.