Table 3.

Adjusted geometric means and 95% confidence intervals for biomarkers of inflammation and adipose-derived hormone concentrations of 746 breast cancer survivors by quartiles of HEI-2005 scores

Postdiagnosis diet quality
Model r2*HEI-2005 quartile 1 (35-57) “Poor”HEI-2005 quartile 2 (57-67) “Mixed”HEI-2005 quartile 3 (67-75) “Mixed”HEI-2005 quartile 4 (75-87) “Better”P for contrast “Better vs. Poor”
n186187187186
C-reactive protein (mg/L)
    Model 10.052.6 (2.1-3.1)2.2 (1.9-2.5)2.1 (1.8-2.5)1.4 (1.2-1.7)<0.0001
    Model 20.302.4 (2.1-2.8)2.0 (1.7-2.3)2.2 (1.9-2.6)1.6 (1.4-1.9)0.0005
    Model 30.302.4 (1.9-2.9)2.0 (1.6-2.4)2.2 (1.8-2.7)1.6 (1.4-2.0)0.004
Serum amyloid A (mg/L)
    Model 10.076.6 (5.9-7.4)5.5 (4.9-6.2)6.2 (5.5-6.9)5.8 (5.2-6.6)0.17
    Model 20.156.5 (5.8-7.2)5.2 (4.8-5.9)6.3 (5.6-7.0)6.1 (5.4-6.8)0.48
    Model 30.156.5 (5.7-7.5)5.4 (4.7-6.2)6.4 (5.5-7.3)6.3 (5.4-7.2)0.63
Leptin (ng/mL)
    Model 10.0121.4 (19.3-23.8)19.5 (17.5-21.6)18.3 (16.5-20.4)17.2 (15.4-19.1)0.004
    Model 20.5820.5 (19.1-21.9)17.8 (16.6-19.0)19.1 (17.8-20.4)19.0 (17.7-20.3)0.13
    Model 30.5919.7 (18.1-21.4)17.4 (16.0-18.9)18.9 (17.4-20.6)19.0 (17.5-20.7)0.63
    Model 40.6019.8 (17.9-21.9)17.2 (15.6-19.1)18.8 (16.9-20.8)18.7 (16.9-20.8)0.36
Adiponectin (μg/mL)
    Model 10.0512.8 (11.7-14.0)13.5 (12.4-14.8)14.0 (12.8-15.3)14.1 (12.9-15.5)0.15
    Model 20.1113.0 (11.9-14.2)14.0(12.8-15.2)13.8 (12.7-15.1)13.7 (12.5-15.0)0.43
    Model 30.1912.7 (11.4-14.1)13.3 (12.0-14.8)12.7 (11.4-14.2)12.6 (11.3-14.1)0.94
    Model 40.1913.0 (11.4-14.7)13.6 (12.0-15.4)13.0 (11.4-14.8)12.9 (11.3-14.7)0.94

NOTE: Model 1: adjusted for age (continuous), energy (kcals/day); model 2: model 1+ BMI (continuous); model 3: model 2+ recreational moderate/vigorous physical activity (continuous), race/ethnicity (non-Hispanic White; Hispanic; Black, African American; American Indian, Asian, other; missing); model 4: model 3+ stage (in situ, localized, regional), menopausal status (premenopausal, postmenopausal, undetermined), smoking (current, former, never, missing).

  • *r2 for models only adjusting for age, energy, and BMI without HEI score were 0.29, 0.14, 0.58 and 0.11 for C-reactive protein, serum amyloid A, leptin, and adiponectin, respectively.