Table 2.

Summary of previously published and publicly accessible data on S49C, S707P, F858L, P1054R, and L1420F

Study (reference)Dork (13)Spurdle (14)Bretsky (15)Stredrick (USRT; ref. 16)Stredrick (Poland; ref. 16)WTCCC (17)
No. cases/controls1,000/5001,453/793110/110856/1,0421,978/2,2861,045/1,476
S49C---1.60 (0.88-2.90)1.87 (1.14-3.11)1.26 (0.81-1.96)
S707P2.4 (1.0-5.6)1.08 (0.59-1.97)0.66 (0.05-5.90)0.47 (0.23-0.93)1.25 (0.80-1.94)0.90 (0.55-1.46)
F858L1.4 (0.7-2.7)-2.02 (0.10-120.15)2.03 (1.05-3.90)1.12 (0.67-1.86)0.66 (0.40-1.10)
P1054R1.4 (0.8-2.2)1.35 (0.85-1.98)0.83 (0.19-3.36)--0.84 (0.58-1.22)
L1420F1.5 (0.9-2.7)-0.66 (0.05-5.90)--0.93 (0.63-1.35)
Combined1.56 (1.11-2.20)1.25 (0.89-1.77)0.75 (0.25-2.25)1.22 (0.84-1.77)1.37 (1.04-1.81)0.96 (0.78-1.18)

Abbreviations: WTCCC, Wellcome Trust Case Control Consortium; USRT, United States Radiologic Technologists study.