Table 1.

Twenty-six prostate cancer risk SNPs identified by GWAS of prostate cancer

SNPChromosomeAssociatedAssociated Allele frequency cases
GeneAlleleAllelesAfrican-AmericanWhite
rs721048*2EHBP1A (10)A, G0.0480.177
rs14656182THADAA (16)A, G0.1430.243
rs126212782ITGA6G (16)A, G0.0090.039
rs26607533IntergenicT (11)C, T0.5430.157
rs76523313FYC01T (25)C, T0.0950.399
rs15459853FYC01G (25)A, G0.2050.406
rs131492904LOC152485T (25)C, T0.2610.233
rs6292424KIAA1211T (25)T, C0.3050.200
rs76796734IntergenicA (16)C, A0.5560.404
rs17021918*4PDL1M5T (16)C, T0.1830.354
rs2511775FCHSD1C (25)T, C0.3710.245
rs93645546SLCC22A3T (11)C, T0.0540.277
rs64656577LMTK2C (16)T, C0.1550.459
rs104865677JAZF1G (9)A, G0.7310.803
rs121551727IntergenicA (16)G, A0.1270.236
rs15122688IntergenicA (16)A, G0.6420.466
rs15718019DAB2IPA (25)C, A0.1450.240
rs1099399410MSMBT (9, 11)C, T0.3900.474
rs496241610CTBP2C (9)T, C0.2010.304
rs1089644911IntergenicG (9)G, A0.6840.570
rs712790011IntergenicA (16)G, A0.3940.200
rs1049251913FAM124AG (25)A, G0.0900.427
rs185996217IntergenicG (11, 16, 17)T, G0.3250.516
rs443079617HNF1B, TCFA (9, 17, 24)G, A0.3530.570
rs273583919KLK2/KLK3G (11)G, A0.3280.138
rs5945572XNUDT10,NUDT11A (10)G, A0.2630.385
  • *rs2710646 used as proxy for rs721048 (r2 = 1); rs3762876 used as a proxy for rs17021918 (r2 = 0.96).