Table 1.

Number of men without and with prostate cancer, RRs for prostate cancer, and RR for death without prostate cancer in men with or without the MetS according to the NCEP and IDF definitions and their respective components and smoking at age 50 over 34 y of follow-up

No prostate cancerProstate cancerPC RR (95% CI)Death without PC RR (95% CI)
MetS (NCEP*), n (%)
    No MetS1,673 (80.3)195 (82.3)ReferenceReference
    MetS284 (13.26)32 (13.5)1.29 (0.89-1.88)1.86 (1.59-2.19)
    Missing data127 (6.1)10 (4.2)
MetS (IDF), n (%)
    No MetS1,755 (84.2)202 (85.2)ReferenceReference
    MetS298 (14.3)32 (13.5)1.18 (0.81-1.71)1.7 (1.46-2.00)
    Missing data31 (1.5)3 (1.3)
Abdominal obesity, >102 cm (NCEP), n (%)
    Not abdominal obesity1,913 (91.8)217 (91.6)ReferenceReference
    Abdominal obesity171 (8.2)20 (8.4)1.31 (0.83-2.08)1.79 (1.48-2.17)
    Missing data0 (0.0)0 (0.0)
Abdominal obesity >94 cm (IDF), n (%)
    No abdominal obesity1,648 (79.1)190 (80.2)ReferenceReference
    Abdominal obesity436 (20.9)47 (19.8)1.11 (0.8-1.52)1.5 (1.31-1.73)
    Missing data0 (0.0)0 (0.0)
Elevated fasting plasma glucose level, ≥6.1 mmol/L (NCEP), n (%)
    No elevated level1,966 (94.3)223 (94.1)ReferenceReference
    Elevated level112 (5.4)12 (5.1)1.18 (0.66-2.11)1.57 (1.23-2.00)
    Missing data6 (0.3)2 (0.8)
Elevated fasting plasma glucose level, ≥5.6 mmol/L (IDF), n (%)
    No elevated level and not DM1,812 (86.9)206 (86.9)ReferenceReference
    Elevated level or DM266 (12.8)29 (12.2)1.04 (0.71-1.54)1.23 (1.04-1.47)
    Missing data6 (0.3)2 (0.8)
Hypertension, ≥130/80 mmHg (NCEP, IDF), n (%)
    No Hypertension724 (34.7)88 (37.1)ReferenceReference
    Hypertension1,359 (65.2)149 (62.9)1.03 (0.79-1.35)1.41 (1.23-1.61)
    Missing data1 (0.0)0 (0.0)
High triglycerides, ≥1.7 mmol/L (NCEP, IDF), n (%)
    Not high triglycerides1,073 (51.5)122 (51.5)ReferenceReference
    High triglycerides1,011 (48.5)115 (48.5)1.15 (0.89-1.48)1.47 (1.3-1.66)
    Missing data0 (0.0)0 (0.0)
Low HDL cholesterol, <1.03 mmol/L (NCEP, IDF), n (%)
    Not Low HDL cholesterol1,357 (65.1)152 (64.1)ReferenceReference
    Low HDL cholesterol344 (16.5)31 (13.1)0.95 (0.65-1.4)1.44 (1.23-1.69)
    Missing data383 (18.4)54 (22.8)
Smoking, n (%)
    Nonsmoker or ex-smoker999 (47.9)138 (58.2)ReferenceReference
    Current smoker1,085 (52.1)99 (41.8)0.84 (0.65-1.08)1.88 (1.65-2.13)

Abbreviation: PC, prostate cancer; DM, diabetes mellitus.

  • *As defined in the NCEP panel III definition of the metabolic syndrome.

  • As defined in the IDF definition of the metabolic syndrome.

  • High-density lipoprotein.