Table 2.

ORs and 95% CIs for risk of prostate cancer associated with the two-way interaction between NAT1/NAT2 and preference for well-done meat

NATPreference for well-done meatCases/controlsOR, adjusted for age and ethnicity (95% CI)*OR, multivariate adjusted (95% CI)
NAT1*10 (copies)
    0No469/4461.001.00
    0Yes395/3950.94 (0.77-1.14)0.92 (0.76-1.12)
    1 or 2No617/6060.97 (0.81-1.26)0.96 (0.80-1.15)
    1 or 2Yes625/6160.95 (0.79-1.14)0.93 (0.78-1.13)
    P for interaction (1 df)0.720.67
NAT2
    Intermediate/rapidNo693/6381.001.00
    Intermediate/rapidYes595/6110.88 (0.75-1.04)0.88 (0.74-1.03)
    SlowNo393/4140.86 (0.72-1.04)0.87 (0.72-1.05)
    SlowYes425/4000.95 (0.79-1.15)0.94 (0.78-1.14)
    P for interaction (1 df)0.080.10
  • *Adjusted for age groups and ethnicity as strata in a conditional logistic regression model.

  • Adjusted for age groups and ethnicity as strata in a conditional logistic regression model and for energy, body mass index, years of education, family history of prostate cancer, and smoking status (never/former/current) as covariates.

  • The P for interaction is based on a Wald test of cross-product terms.