Table 3.

Association between ovarian cancer characteristics and anti-MUC1 antibodies among 117 cases from the Nurses' Health Studies

N (%)Geometric mean*P
Anti-MUC1 antibody0.54
Age at blood draw (quartiles), y
    <5125 (21)0.52
    51-5634 (29)0.50
    57-6331 (27)0.52
    64+27 (23)0.630.28
Invasiveness
    Borderline12 (11)0.49
    Invasive99 (89)0.530.65
Histologic type
    Serous borderline6 (6)0.540.89
    Serous invasive63 (66)0.52Ref.
    Mucinous12 (13)0.430.33
    Endometrioid11 (11)0.520.96
    Clear cell4 (4)0.540.88
Stage
    Early (stages I-II)40 (35)0.45
    Late (stages III-IV)75 (65)0.590.04
Time between blood draw and diagnosis, mo
    36-7729 (25)0.38
    78-10229 (25)0.59
    103-13529 (25)0.53
    136+30 (25)0.700.01
  • *Adjusted for age at blood collection in years (continuous) and by assay plate (indicators).

  • P-trend from linear regression modeling dichotomous and ordinal variables linearly or as indicators for histologic type, adjusting for age (continuous) and assay plate (indicators).