Table 5.

Relative risks of breast cancer mortality with 95% CIs obtained in Cox regression analyses

ExposureCohort-specific quintilesMean (SD)Total no. of casesRR (95% CI)*Attained age (y)
<50≥50
RR (95% CI)*RR (95% CI)*
BMI120.0 (1.2)1041.00 (reference)1.00 (reference)1.00 (reference)
222.2 (0.8)1020.86 (0.63-1.16)0.73 (0.38-1.40)0.87 (0.61-1.23)
324.1 (0.8)1320.99 (0.74-1.32)0.85 (0.45-1.63)0.98 (0.70-1.37)
426.4 (1.0)1470.99 (0.74-1.32)1.11 (0.59-2.09)0.93 (0.67-1.29)
531.7 (3.6)1480.99 (0.74-1.32)1.22 (0.64-2.31)0.92 (0.66-1.27)
Ptrend0.70.30.8
Systolic BP1105.4 (5.8)941.00 (reference)1.00 (reference)1.00 (reference)
2115.4 (2.9)701.07 (0.60-1.92)1.25 (0.38-4.17)0.99 (0.51-1.93)
3122.7 (3.0)1101.03 (0.61-1.72)1.80 (0.60-5.39)0.84 (0.46-1.51)
4133.6 (4.8)1631.64 (1.00-2.69)2.52 (0.83-7.63)1.38 (0.79-2.39)
5156.3 (16.1)1961.54 (0.93-2.56)2.49 (0.73-8.50)1.33 (0.76-2.33)
Ptrend0.060.060.2
Diastolic BP163.5 (5.5)861.00 (reference)1.00 (reference)1.00 (reference)
270.4 (3.4)791.08 (0.59-1.98)0.79 (0.21-2.99)1.12 (0.57-2.20)
377.0 (3.6)1581.40 (0.83-2.36)2.20 (0.74-6.59)1.20 (0.67-2.17)
481.0 (3.5)1101.54 (0.87-2.71)1.60 (0.46-5.56)1.45 (0.77-2.74)
592.6 (7.7)2002.10 (1.24-3.54)2.93 (0.90-9.58)1.88 (1.05-3.38)
Ptrend0.0020.050.01
Glucose14.1 (0.5)961.00 (reference)1.00 (reference)1.00 (reference)
24.7 (0.3)1121.64 (0.60-4.49)0.48 (0.05-4.45)2.26 (0.72-7.07)
35.0 (0.3)1382.48 (0.94-6.54)0.67 (0.08-5.88)3.44 (1.15-10.26)
45.4 (0.3)1453.27 (1.25-8.57)2.36 (0.31-17.83)3.68 (1.23-11.01)
56.6 (1.7)1422.41 (0.91-6.36)0.85 (0.09-8.01)3.13 (1.05-9.32)
Ptrend0.10.80.1
Cholesterol14.2 (0.4)1051.00 (reference)1.00 (reference)1.00 (reference)
24.9 (0.2)1080.84 (0.56-1.27)0.89 (0.39-2.01)0.79 (0.49-1.28)
35.5 (0.3)1080.67 (0.44-1.02)0.84 (0.36-1.94)0.60 (0.37-0.97)
46.1 (0.3)1350.77 (0.52-1.15)0.79 (0.33-1.91)0.72 (0.46-1.14)
57.3 (0.9)1710.81 (0.55-1.21)0.46 (0.16-1.31)0.82 (0.53-1.28)
Ptrend0.50.080.8
Triglycerides10.6 (0.1)881.00 (reference)1.00 (reference)1.00 (reference)
20.9 (0.1)1141.37 (0.78-2.39)1.13 (0.31-4.08)1.39 (0.75-2.60)
31.1 (0.1)1271.46 (0.85-2.53)2.35 (0.71-7.77)1.30 (0.70-2.41)
41.5 (0.2)1251.17 (0.67-2.04)2.10 (0.61-7.21)1.03 (0.55-1.92)
52.5 (1.1)1621.62 (0.93-2.80)2.11 (0.58-7.65)1.53 (0.83-2.82)
Ptrend0.20.30.3
  • *Stratified for cohort and adjusted for year of birth, age at measurement, smoking, and quintile levels of BMI (except BMI). RRs are corrected for RDR; conversion into uncorrected RR = exp[log(RR)*RDR]. RDR: BMI, 0.90; systolic BP, 0.54; diastolic BP, 0.51; glucose, 0.27; cholesterol, 0.66; triglycerides, 0.50.