Table 5.

Mean and 95% CI for BMC and BMD at follow-up in DISC intervention and usual care groups

Intervention groupUsual care groupP*
nMean (5-95% CI)nMean (5-95% CI)
BMC (g)
    Unadjusted1092,450 (2,352-2,548)1062,378 (2,279-2,477)0.13
    Adjusted (excluding current diet)1092,444 (2,389-2,499)1062,377 (2,321-2,432)0.02
    Adjusted (including current diet)1022,448 (2,395-2,502)1012,356 (2,302-2,410)0.003
BMD (g/cm2)
    Unadjusted1091.18 (1.16-1.21)1061.16 (1.14-1.19)0.08
    Adjusted (excluding current diet)1091.18 (1.16-1.21)1061.16 (1.14-1.19)0.07
    Adjusted (including current diet)1021.19 (1.16-1.21)1011.16 (1.14-1.18)0.01
  • *P values from Wald test using linear mixed-effects regression.

  • Adjusted for height, total body mass from DXA, type of DXA machine, BMI at baseline (Z-score), age at visit, age at randomization, race, smoking status, education, leisure physical activity at 14 to 17 y old and during the past year, hormonal contraceptive use, and number of full-term pregnancies.

  • Adjusted for height, total body mass from DXA, type of DXA machine, BMI at baseline (Z-score), age at visit, age at randomization, race, smoking status, education, leisure physical activity at 14 to 17 y old and during the past year, hormonal contraceptive use, number of full-term pregnancies, current intake of energy (kcal), % saturated fat, % monounsaturated fat, % polyunsaturated fat, cholesterol (mg/1,000 kcal), insoluble fiber (g/1,000 kcal), soluble fiber (g/1,000 kcal), calcium (mg), and vitamin D (μg).