Table 3.

Medians (interquartile ranges) of serum adiponectin, leptin, C-peptide, and homocysteine concentrations at T1 in the control arm of the PPT, by adenoma recurrence at T4

OutcomenAdiponectin (ng/mL)P*nLeptin (ng/mL)P*nC-peptide (ng/mL)P*nHomocysteine (μmol/L)P*
Median (IQR)Median (IQR)Median (IQR)Median (IQR)
Total6273.16 (1.94-5.10)6279.31 (4.63-17.4)6231.37 (0.98-1.80)62513.0 (10.8-15.7)
No polyp2773.29 (2.03-5.56)27710.5 (5.89-20.7)2741.34 (0.96-1.80)27612.5 (10.5-14.7)
Nonadenomatous polyps only1082.97 (1.60-5.21)0.291087.22 (3.55-19.6)0.061071.32 (0.92-1.69)0.8010713.4 (10.8-16.4)0.02
Any adenoma2423.08 (1.82-4.74)0.152427.79 (4.30-13.9)0.00082421.42 (1.05-1.88)0.0624213.7 (11.2-16.3)0.0004
One adenoma1403.14 (1.88-4.60)0.331404.68 (4.29-13.2)0.0021401.41 (1.00-1.85)0.2614013.6 (11.1-16.3)0.006
Multiple adenoma1022.98 (1.80-4.80)0.171028.16 (4.35-14.0)0.031021.45 (1.15-1.97)0.0510213.8 (11.4-16.1)0.003
Low-risk adenoma1743.14 (1.78-4.84)0.261747.76 (4.49-14.2)0.0041741.39 (1.03-1.80)0.3417413.6 (11.1-16.3)0.004
High-risk adenoma683.03 (1.98-4.60)0.21687.92 (3.86-13.3)0.02681.52 (1.16-2.00)0.016814.4 (11.6-16.2)0.003
Nonadvanced adenoma2093.10 (1.80-4.80)0.222098.15 (4.35-14.1)0.0022091.41 (1.08-1.83)0.0920913.7 (11.4-16.2)0.0007
Advanced adenoma333.03 (2.01-4.03)0.25337.34 (3.87-12.9)0.04331.46 (0.99-2.03)0.243314.2 (11.1-16.6)0.07
  • *All comparisons against the no-polyp group using Wilcoxon rank-sum test.

  • *All comparisons against the no-polyp group using Wilcoxon rank-sum test.