Comparison of the prevalence of current drinkers consuming over the weekly drinking recommendations, and consuming harmful weekly amounts of alcohol, among survivors and the general population of Britain, overall and for childhood cancer and treatment subgroups, with ORs and 99% CIs from multivariable GEE logistic regression models
| Childhood cancer type group and treatment subgroup where relevant | Numbers used* | Consuming over recommendations | Consuming harmful amounts of alcohol | ||
|---|---|---|---|---|---|
| Percentage* | OR (99% CI)† | Percentage* | OR (99% CI)† | ||
| GHS (referent) | 10,868‡ | 25.9%‡ | 1.00 | 6.0%‡ | 1.00 |
| All survivors | 7,972 | 23.8% | 0.65 (0.58-0.73) | 3.9% | 0.40 (0.32-0.49) |
| Brain irradiated | 2,149§ | 20.4% | 0.52 (0.43-0.62) | 2.6% | 0.24 (0.16-0.36) |
| Brain not irradiated | 3,734§ | 24.6% | 0.78 (0.69-0.89) | 3.8% | 0.47 (0.36-0.61) |
| CNS neoplasm | 1,457 | 19.1% | 0.50 (0.41-0.62) | 3.0% | 0.33 (0.21-0.51) |
| Brain irradiated | 628§ | 15.0% | 0.38 (0.27-0.53) | 1.9% | 0.21 (0.09-0.48) |
| Brain not irradiated | 535§ | 23.9% | 0.75 (0.56-1.02) | 3.0% | 0.37 (0.19-0.74) |
| Leukemia | 2,135 | 22.3% | 0.54 (0.45-0.64) | 3.5% | 0.30 (0.21-0.43) |
| Brain irradiated | 1,487§ | 22.9% | 0.58 (0.48-0.71) | 2.9% | 0.26 (0.16-0.41) |
| Brain not irradiated | 136§ | 19.9% | 0.55 (0.29-1.04) | 3.7% | 0.30 (0.06-1.42) |
| Hodgkin's lymphoma | 629 | 33.2% | 1.10 (0.86-1.40) | 4.3% | 0.44 (0.25-0.79) |
| Non–Hodgkin's lymphoma | 452 | 29.0% | 0.81 (0.60-1.10) | 5.5% | 0.52 (0.28-0.94) |
| Neuroblastoma | 319 | 23.5% | 0.59 (0.40-0.87) | 3.8% | 0.38 (0.17-0.86) |
| Wilms' tumor | 784 | 27.7% | 0.83 (0.66-1.05) | 4.3% | 0.47 (0.29-0.77) |
| Bone sarcomas | 341 | 21.7% | 0.62 (0.43-0.91) | 4.7% | 0.61 (0.30-1.24) |
| Soft tissue sarcomas | 592 | 27.7% | 0.78 (0.60-1.03) | 6.8% | 0.74 (0.46-1.19) |
| Retinoblastoma | 564 | 21.3% | 0.64 (0.48-0.86) | 3.2% | 0.39 (0.20-0.76) |
| Other neoplasms | 699 | 22.2% | 0.64 (0.49-0.84) | 3.3% | 0.36 (0.19-0.66) |
↵*The totals and percentages were calculated for survivors aged ≤69 years.
↵†From a GEE multivariable logistic regression model controlling for age at questionnaire completion (≤69 years), gender, legal marital status, SEC, educational attainment, and region, and took into account the GHS weighting factor, for the likelihood of consuming over the recommendations for weekly alcohol units or consuming harmful weekly amounts of alcohol.
↵‡These are the unweighted values from the GHS. Using the GHS weighting factor, the weighted percentage of those consuming over recommended levels and consuming harmful weekly amounts of alcohol from the GHS were 26.6% and 6.3%, respectively.
↵§These do not sum the total number of survivors used because the category brain not irradiated does not include the survivors for whom we have no record of their radiotherapy; this was for all survivors (n = 2,089), for CNS neoplasm survivors (n = 294), and for leukemia survivors (n = 512).