Table 4.

Risk of gastric lesions related to the Val16Ala polymorphism by serum H. pylori IgG titer

MnSOD GenotypeIgG titerNormal, SG, mild CAGSevere CAGIMDYS
n (%)n (%)OR (95% CI)*n (%)OR(95% CI)n (%)OR (95% CI)
Val/Val<1479 (33.2)15 (11.3)1.00227 (17.3)1.0081 (18.0)1.00
Val/Ala+Ala/Ala<1204 (14.2)8 (6.1)1.32 (0.55-3.21)80 (6.1)0.80 (0.58-1.09)35 (7.8)0.96 (0.61-1.50)
Val/Val1∼2.94289 (20.0)36 (27.3)3.96 (2.09-7.51)361 (27.4)2.82 (2.25-3.54)122 (27.1)3.02 (2.15-4.24)
Val/Ala+Ala/Ala1∼2.94101 (7.0)14 (10.6)4.49 (2.06-9.75)137 (10.4)3.30 (2.42-4.51)46 (10.2)3.44 (2.19-5.39)
Val/Val>2.94289 (20.0)49 (37.1)5.37 (2.90-9.94)381 (29.0)3.05 (2.43-3.82)107 (23.8)2.60 (1.84-3.67)
Val/Ala+Ala/Ala>2.9481 (5.6)10 (7.6)4.00 (1.71-9.34)129 (9.8)3.87 (2.79-5.37)59 (13.1)5.59 (3.59-8.68)
  • *Adjusted for age, gender, smoking status, and drinking status.