Table 2.

Genotype frequencies of the Val16Ala polymorphism in different groups

SubjectsNormal, SG, mild CAGSevere CAGIMDYS
n (%)n (%)OR (95% CI)*n (%)OR (95% CI)*n (%)OR (95% CI)*
Val/Val1,065 (73.2)100 (75.2)1.00970 (73.7)1.00312 (69.0)1.00
Val/Ala364 (25.1)31 (23.3)1.00 (0.65-1.54)320 (24.3)1.02 (0.85-1.23)127 (28.1)1.27 (0.98-1.64)
Ala/Ala25 (1.7)2 (1.5)1.12 (0.25-4.93)26 (2.0)1.33 (0.74-2.38)13 (2.9)1.90 (0.90-4.02)
Val/Ala+Ala/Ala389 (26.8)33 (24.8)1.01 (0.66-1.53)346 (26.3)1.04 (0.87-1.24)140 (31.0)1.31 (1.02-1.68)
  • *Adjusted for age, gender, H. pylori infection, smoking status, and drinking status.