Table 3.

Parameter estimate in the one susceptibility type (sporadic) model, incorporating various residual familial associations by MLM (δFM = 0)

ParametersFamilial association components
δFO = δMO = δSS = 0δFO = δMO = δSSδFO = δMO, δSSδFO, δMO, δSS
β (SE)−4.58 (0.14)−4.80 (0.17)−4.72 (0.17)−4.73 (0.17)
ξsex (SE)*−1.11 (0.22)−1.09 (0.22)−1.09 (0.22)−1.09 (0.22)
ξfounder (SE)−1.72 (0.33)−1.65 (0.33)−1.56 (0.34)−1.56 (0.34)
δFO (SE)00.36 (0.19)0.07 (0.22)0.07 (0.23)
δMO (SE)00.36 (0.19)0.07 (0.22)0.11 (0.44)
δSS (SE)00.36 (0.19)0.51 (0.24)0.51 (0.24)
−2ln(L)1,359.451,353.001,350.381,350.37
d.f.3456
P§0.0280.2690.920
P0.0110.106
AIC1,365.451,361.001,360.381,362.37
  • *Sex value for male is 0 and for female is 1.

  • Founder value for founder is 1 and for nonfounder is 0.

  • Number of functionally independent parameters estimated.

  • §Compared with model (δFO, δMO, δSS).

  • Compared with model (δFO = δMO, δSS).