Table 1.

Distribution of rs2295190 genotypes by case-control status, and Hardy-Weinberg equilibrium P values for controls, by study population

StudyCase/control genotype*T allele frequency, controlsPHWE
GGGTTT
Initial three studies
    DOV329/483141/16216/120.1420.87
    HOP214/49777/1663/80.1360.19
    USC258/41780/11710/40.1160.21
Twelve additional studies
    AUS617/789236/29523/160.1490.06
    GER148/30252/1113/140.1630.37
    HAW45/11023/461/20.1580.37
    MAL281/546143/22315/250.1720.71
    MAY193/26274/997/50.1490.30
    NCO446/559155/1699/100.1280.62
    NEC449/682145/20011/190.1320.31
    POL160/40887/1647/170.1680.88
    SEA675/893244/29118/290.1440.35
    STA191/12972/483/40.1551.00
    UCI203/33164/7911/100.1180.06
    UKO336/411122/13310/190.1520.05

NOTE: Restricted to non-Hispanic white women.

  • *Invasive cases only.