Table 4.

Mean adjusted estimates and 95% CI of PSADT after recurrence among men with diabetes at surgery stratified by race and obesity

No. of patientsMean adjusted PSADT* (95% CI)PPinteraction by racePinteraction by obesity
TotalDiabeticDiabetic at surgeryNot diabetic at surgery
Overall1923323.4 (15.7-34.8)16.7 (13.0-21.4)0.120.11
White991516.4 (8.8-30.3)18.7 (12.8-27.3)0.710.75
    Nonobese69520.6 (7.4-57.5)19.8 (12.7-30.9)0.94
    Obese301011.0 (4.8-25.0)22.7 (9.6-53.7)0.24
Black931829.3 (17.0-50.5)14.9 (10.6-21.0)0.020.87
    Nonobese611142.5 (20.3-89.0)21.6 (13.7-34.1)0.06
    Obese32727.5 (11.3-67.1)9.6 (6.0-15.3)0.02

NOTE: Using log-transformed PSADT as a continuous variable in a linear regression model. Obesity was defined as a BMI ≥ 30 kg/m2.

  • *Adjusted for age, year of surgery, race, BMI, clinical stage, biopsy Gleason score, center, and preoperative PSA.

  • Pinteraction by race assessed by including the cross-product term between diabetes and race in the model.

  • Pinteraction by obesity assessed by including the cross-product term between diabetes and obesity in the model.