Table 3.

Relative risk and 95% CI of time to biochemical progression after radical prostatectomy among men with diabetes at surgery stratified by race and obesity

No. total patientsNo. diabeticsHR* (95% CI)PPinteraction by racePinteraction by obesity
Overall§1,2402260.94 (0.72-1.23)0.670.09
White659991.24 (0.84-1.85)0.280.006
    Nonobese479550.69 (0.36-1.32)0.26
    Obese180442.52 (1.40-4.54)0.002
Black5811270.79 (0.55-1.14)0.210.91
    Nonobese402710.75 (0.45-1.25)0.27
    Obese179560.89 (0.52-1.54)0.68

NOTE: Obesity was defined as a BMI ≥ 30 kg/m2.

  • *Adjusted for age, year of surgery, race, BMI, clinical stage, biopsy Gleason score, center, and preoperative PSA.

  • Pinteraction by race assessed by including the cross-product term between diabetes and race in the model.

  • Pinteraction by obesity assessed by including the cross-product term between diabetes and obesity in the model.

  • §Twenty-two men were missing follow-up and were not included in these analyses.