Table 3.

Associations between rs9642880 T allele and bladder cancer risk by strata of selected risk factors

Non-Hispanic whiteChineseNon-Hispanic white and Chinese
Cases/controlsRR (95% CI)PCases/controlsRR (95% CI)PRR (95% CI)P
Age at diagnosisa
  Younger270/3171.35 (1.05–1.74)0.021305/2721.13 (0.88–1.46)0.34
  Older239/2851.52 (1.16–2.00)0.0021236/2631.27 (0.95–1.69)0.10
  P interaction0.570.52
Gendera
  Male401/4851.41 (1.17–1.70)0.0031429/4121.20 (0.99–1.45)0.0581.31 (1.15–1.49)0.00068
  Female108/1171.68 (1.09–2.59)0.019112/1231.35 (0.89–2.04)0.151.50 (1.12–2.02)0.0069
  P interaction0.380.530.30
Smoking historyb
  Never95/2171.74 (1.21–2.50)0.0026182/2381.23 (0.91–1.68)0.181.43 (1.13–1.81)0.0026
  Former193/2591.57 (1.18–2.09)0.002176/861.44 (0.87–2.38)0.151.54 (1.20–1.97)0.00071
  Current221/1060.98 (0.70–1.39)0.93283/2111.12 (0.85–1.48)0.481.06 (0.86–1.32)0.58
  P trend0.0220.760.46
  P interaction0.0550.510.32
NSAID use
  Nonusers313/3551.27 (1.01–1.62)0.045
  Users190/2451.58 (1.16–2.14)0.0038
  P interaction0.17
Stage/gradea  Ta/G1-2c284/6021.64 (1.32–2.03)
   All other stage/graded218/6021.19 (0.95–1.50)
  • aAdjusted for smoking.

  • bAdjusted for age and gender.

  • c“Low probability of progression” as defined by Kiemeney et al (14).

  • d“High probability of progression” as defined by Kiemeney et al (14).