Table 6.

Characteristics of study populations used in the meta-analysis of rs719725 and colorectal tumor riska

StudyPopulationLocationCasesControlsMAFHWE% female
Zanke et al.OntarioCanada1,2261,239
NewfoundlandCanada452367
SeattleWashington687688
Scotland-3Scotland9751,002
Scotland-4Scotland1,9101,985
France-NantesFrance1,0681,113
France-FamilialFrance370539
EPICEurope761749
Poynter et al.Clinic-basedUSA, Canada, Australia288505Ok51.6
Population-basedUSA, Canada, Australia1,3442,196Ok54.0
Curtin et al.UtahUtah438439∼370.13∼50
SheffieldUnited Kingdom405403∼370.14∼50
LeedsUnited Kingdom249218∼370.78∼50
PresentWHI40 US centers65666434.80.53100
 studyDALSCalifornia, Utah, Minnesota1,4611,81337.00.1845.5
MinnCCSMinnesota51762836.30.8350.7
PLCO10 U.S. centers1,2571,38538.70.2635.8
  • aA dash (-) indicates that data was not reported; Ok: Poynter et al. report that all SNPs were in HWE, but do not describe their cutoff value. All studies were of cancer except for MinnCCS and PLCO, which were of adenoma.