Table 4.

Association between 9p24 risk locus rs719725 and colorectal tumor, stratified by sexa

ColorectalColonRectum
StudySexOR95% CIOR95% CIOR95% CI
WHIFemale1.191.01–1.401.150.97–1.371.381.01–1.88
  (Cancer)
DALSOverall1.000.91–1.11
  (Cancer)Male1.020.89–1.17
Female0.980.84–1.13
MinnCCSOverall0.980.82–1.171.020.84–1.250.860.60–1.23
(Adenoma)Male0.900.71–1.150.900.69–1.171.000.61–1.63
Female1.080.83–1.411.240.91–1.700.680.40–1.17
PLCOOverall1.110.99–1.251.141.00–1.291.060.87–1.30
(Adenoma)Male1.110.96–1.281.130.96–1.321.150.87–1.51
Female1.090.90–1.321.130.91–1.410.950.70–1.29
  • aModels are adjusted for age and study center, as appropriate. For colon- and rectum-specific analyses, excluded cases where tumor location was unknown (WHI 3, MinnCCS 4, PLCO 17) or in both the colon and the rectum (MinnCCS 103, PLCO 148).