Table 3.

Association of β-catenin expression and molecular markers

Membrane H1Cytoplasmic H2MTC H3
N.PPP
Cell cycle markers
Cyclin D1Rho −0.113Rho −0.154Rho 0.019
0.06250.0108*0.7568
Cyclin E1Rho 0.344Rho 0.364Rho 0.217
<0.0001*<0.0001*0.0003*
p21Rho 0.041Rho −0.018Rho 0.086
0.49710.76040.1515
p27Rho −0.231Rho −0.363Rho 0.124
0.0001*<0.0001*0.0407*
Notch1
    <67%133
    >67%*930.0077*<0.0001*0.1731
PI3K/AKT pathway
    PIK3CA
        Wt146
        Mut*120.18060.48050.0528*
    PIK3CA
        No change174
        Amp280.93750.18850.1342
    PTEN
        H >0181
        H = 0*700.0232*<0.0001*0.0599*
    pAKT
        H <22191
        H >22600.52740.87690.7144
    PI3K/AKT
        Wt53
        Altered*1340.27980.09890.0057*

*Significantly associated with β-catenin expression.