Table 3.

Association of β-catenin expression and molecular markers

		Membrane H1	Cytoplasmic H2	MTC H3
	N.	P	P	P
Cell cycle markers
Cyclin D1		Rho −0.113	Rho −0.154	Rho 0.019
		0.0625	0.0108*	0.7568
Cyclin E1		Rho 0.344	Rho 0.364	Rho 0.217
		<0.0001*	<0.0001*	0.0003*
p21		Rho 0.041	Rho −0.018	Rho 0.086
		0.4971	0.7604	0.1515
p27		Rho −0.231	Rho −0.363	Rho 0.124
		0.0001*	<0.0001*	0.0407*
Notch1
<67%	133
>67%*	93	0.0077*	<0.0001*	0.1731
PI3K/AKT pathway
PIK3CA
Wt	146
Mut*	12	0.1806	0.4805	0.0528*
PIK3CA
No change	174
Amp	28	0.9375	0.1885	0.1342
PTEN
H >0	181
H = 0*	70	0.0232*	<0.0001*	0.0599*
pAKT
H <22	191
H >22	60	0.5274	0.8769	0.7144
PI3K/AKT
Wt	53
Altered*	134	0.2798	0.0989	0.0057*

*Significantly associated with β-catenin expression.