Table 2.

Cross-correlations among exposure biomarkers in menthol and regular cigarette smokers

CharacteristicCPDMenthol scorePlasma nicotinePlasma cotinineUrine total PAHUrine mentholUrine NNALUrine nic equiv
Menthol smoker
  CPD1.00.080.26b 0.250.170.020.050.11
  Menthol score1.00.160.040.100.050.050.05
  Plasma nicotine1.00.71a 0.46b 0.44b 0.250.54a
  Plasma cotinine1.00.41b 0.34b 0.44b 0.57a
  Urine total PAH1.00.55a 0.48a 0.80a
  Urine menthol1.00.30b 0.60a
  Urine NNAL1.00.45b
Urine nic equiv1.0
Regular smoker
  CPD1.00.170.170.140.30b0.060.35b 0.25b
  Menthol score1.00.010.070.090.30b 0.050.05
  Plasma nicotine1.00.82a 0.43b 0.160.39b 0.63a
  Plasma cotinine1.00.34b 0.150.43b 0.63a
  Urine PAH total1.00.45b 0.43b 0.75a
  Urine menthol1.00.150.36b
  Urine NNAL1.00.67a
  Urine nic equiv1.0
  • aSignificant P < 0.0001.

  • bSignificant P < 0.05.