Table 4.

Logistic regression analysis with HbA1c quartile as exposure in 2-year intervals (study 1: Adenoma anywhere in colon)a

HbA1c quartileAdjusted ORb(95% CI)
Prior year 1–2Prior year 3–4Prior year 5–6Prior year 7–8Prior year 9–10
Any adenomaAdvanced adenomaAny adenomaAdvanced adenomaAny adenomaAdvanced adenomaAny adenomaAdvanced adenomaAny adenomaAdvanced adenoma
3.40–6.90Reference n = 403Reference n = 148Reference n = 291Reference n = 110Reference n = 224Reference n = 86Reference n = 131Reference n = 57Reference n = 61Reference n = 24
6.91–7.781.0 (0.9–1.2) n = 3491.2 (0.9–1.6) n = 1411.1 (0.9–1.4) n = 3011.3 (0.9–1.7) n = 1261.0 (0.8–1.3) n = 2461.0 (0.7–1.5) n = 971.2 (0.9–1.7) n = 1260.9 (0.6–1.5)n = 400.9 (0.6–1.4)n = 580.9 (0.5–1.8)n = 24
7.79–8.901.0 (0.8–1.2)n = 2761.1 (0.8–1.5)n = 1021.0 (0.8–1.2)n = 2830.9 (0.6–1.3)n = 960.8 (0.7–1.1)n = 2450.8 (0.6–1.2)n = 931.0 (0.7–1.4)n = 1411.1 (0.7–1.7)n = 611.0 (0.6–1.5)n = 660.8 (0.4–1.5)n = 20
8.91–17.91.1 (0.9–1.4)n = 2191.1 (0.7–1.6)n = 711.2 (0.9–1.5)n = 2911.2 (0.8–1.7)n = 1031.0 (0.7–1.3)n = 2930.9 (0.6–1.3)n = 951.0 (0.8–1.4)n = 1911.0 (0.6–1.6)n = 741.1 (0.7–1.7)n = 1231.3 (0.7–2.4)n = 55
Missing0.9 (0.6–1.3)n = 490.8 (0.4–1.4)n = 161.3 (1.0–1.7)cn = 1301.2 (0.8–1.8)n = 431.0 (0.8–1.3)n = 2881.1 (0.7–1.5)n = 1071.1 (0.8–1.5)n = 7071.0 (0.7–1.6)n = 2460.8 (0.5–1.1)n = 9880.9 (0.5–1.5)n = 355
  • aPatients without any adenoma as controls.

  • bAdjusted for sex, age, ethnicity, BMI, income status, year of large bowel endoscopy, duration of diabetes, NSAID use, aspirin use, statin use, and acid-suppressive medication use.

  • cP < 0.05.