Table 1.

Characteristics of the cases and controls

Study 1: Adenoma anywhere in the colonStudy 2: Distal adenoma
Cases (N = 1,296)Controls (N = 2,952)Cases (N = 951)Controls (N = 8,862)
Female, %41493746
Age (median, IQR), y,71 (65–77)71 (64–77)67 (60–74)66 (60–73)
Race, %
  White60595752
  Black14121216
  Hispanic12121213
  Asian10111414
  Other  2  3  2  3
  Missing  2  3 2 3
BMI, %
  ≤2517171617
  >25 to 3036343834
  >3036383637
  Missing10111012
Socioeconomic status, %
  Below median49474245
  Median or above49505552
  Missing  3  3  2  3
Diabetes duration, %
  <5 y26303433
  5 to <10 y25232524
  ≥10 y39403235
  Missing10  8  9  9
Concomitant medications,a %
  NSAIDs12171115
  Aspirin  2  2  1  1
  Proton pump inhibitor  4  6  2  3
  Statin38383234
Most recent lower endoscopy during 1995–1998, %
  Colonoscopy ≤3 y priorb  5  5  1  1
  Sigmoidoscopy ≤3 y priorb  5  5  1  3
  Colonoscopy >3 y priorb1919  3  3
  Sigmoidoscopy >3 y priorb19221116
  None53498478
  Lower endoscopy with polypectomy 1995–1998, %1816  5  4
  • aAt least 1 year of cumulative use and use within 1 year of the index date.

  • bPrior to index date.