Table 1.

Association of change in physical activity with colon cancer incidence and mortality, CPS II

Physical activityColon cancer incidenceColon cancer mortality
Number of casesAge-adjusted HR (95% CI)Multivariablea HR (95% CI)Multivariableb HR (95% CI)Number of casesAge-adjusted HR (95% CI)Multivariablea HR (95% CI)Multivariableb HR (95% CI)
Change from 1982 to 1997 based on z-score of activity1,3860.94 (0.86–1.02)0.95 (0.87–1.03)6020.92 (0.81–1.04)0.93 (0.81–1.05)0.93 (0.81–1.05)0.92 (0.81–1.05)
Change from 1982 to 1992
   Increasing780.99 (0.78–1.28)1.02 (0.80–1.30)1.04 (0.81–1.33)411.03 (0.74–1.45)1.05 (0.74–1.47)1.08 (0.77–1.51)
   Decreasing9831.10 (0.97–1.24)1.08 (0.96–1.22)1.11 (0.98–1.25)4190.91 (0.76–1.08)0.88 (0.74–1.05)0.91 (0.77–1.09)
   Consistently high4341.01 (0.88–1.16)1.02 (0.89–1.17)1.07 (0.93–1.23)1800.81 (0.66–0.99)0.82 (0.66–1.00)0.86 (0.69–1.06)
   Consistently low368referencereferencereference186referencereferencereference
  • aAdjusted for sex, education, smoking, use of postmenopausal hormones (among women only), intake of multivitamin, red meat, folate, alcohol, NSAIDs, fiber, calcium, and total energy.

  • bAdjusted for above plus BMI.