Table 3.

IRR of BCC, CMM, MCC, and SCC according to any use of specific photosensitizing medications for ST use

Medications for ST useBCCCMMMCCSCC
No. casesIRR (95% CI)*No. casesIRR (95% CI)*No. casesIRR (95% CI)*No. casesIRR (95% CI)*
Any use of ST medications12,8311.34 (1.31-1.37)2,5581.11 (1.06-1.16)301.42 (0.93-2.15)2,3321.47 (1.40-1.54)
Antimicrobials
    Acyclovir1,9541.3 (1.3-1.4)3681.1 (1.0-1.2)41.1 (0.4-2.9)4081.5 (1.4-1.7)
    Ciprofloxacin3,1701.2 (1.1-1.2)5571.0 (0.9-1.1)111.4 (0.8-2.7)7091.3 (1.2-1.4)
    Doxycycline1,7441.3 (1.2-1.3)3651.1 (1.0-1.2)41.5 (0.5-4.0)2801.3 (1.2-1.5)
    Ketoconazole4,0561.5 (1.4-1.5)7541.1 (1.0-1.2)91.5 (0.7-2.9)7411.5 (1.4-1.7)
    Levofloxacin361.5 (1.1-2.1)30.6 (0.2-1.9)051.0 (0.4-2.3)
    Sulfamethazole with trimethoprim4161.1 (1.0-1.2)661.0 (0.8-1.2)11.0 (0.1-6.9)1211.7 (1.4-2.0)
    Tetracycline1,7231.3 (1.3-1.4)3711.1 (1.1-1.3)20.8 (0.2-3.1)3051.5 (1.4-1.7)
Antimalarials
    Hydroxychloroquine2,6291.4 (1.3-1.4)6011.2 (1.1-1.3)20.9 (0.2-3.6)3001.4 (1.3-1.6)
SDA
    Acitretin631.1 (0.8-1.4)141.2 (0.7-2.0)17.8 (1.1-56)414.1 (3.0-5.6)
    Isotretinoin1322.0 (1.7-2.4)551.3 (1.0-1.8)122.6 (3.1-166)102.1 (1.1-3.8)

Abbreviation: SDA, systemic dermatologic agents.

  • *Adjusted for age, period, sex, and education. The reference group is never users of the specific photosensitizing medication.