Table 2.

IRR of BCC, CMM, MCC, and SCC per 5 y of treatment with specific photosensitizing medications for LT daily use, among users of such medications

Medications for LT daily useIRR (95% CI)*
BCCCMMMCCSCC
Any LT medication use0.99 (0.99-1.00)0.99 (0.98-1.01)1.08 (1.00-1.17)1.03 (1.02-1.04)
Diuretic agents
    Bendroflumethiazide0.9 (0.7-1.2)1.3 (0.8-2.2)1.5 (0.9-2.4)
    Bumetanide1.0 (0.8-1.2)1.4 (0.8-2.2)1.3 (0.9-1.8)
    Furosemide0.9 (0.9-1.0)1.0 (0.8-1.1)1.6 (0.9-2.7)1.1 (1.0-1.2)
Nonsteroidal anti-inflammatory drugs
    Diclofenac1.0 (0.9-1.1)0.8 (0.6-1.1)0.4 (0.02-6.8)0.8 (0.6-1.1)
    Ibuprofen0.9 (0.9-1.0)0.9 (0.7-1.0)0.1 (0.01-1.4)1.0 (0.8-1.1)
    Indomethacin0.9 (0.7-1.1)1.3 (0.8-2.0)0.3 (0.01-12)1.2 (0.9-1.8)
Cardiovascular medications
    Amiodarone1.0 (0.7-1.4)1.6 (0.8-3.2)1.4 (0.8-2.5)
    Atenolol1.0 (1.0-113)1.2 (1.0-1.4)1.3 (0.4-4.5)1.3 (1.1-1.5)
    Captopril0.9 (0.8-1.0)1.0 (0.7-1.5)0.7 (0.1-5.5)0.9 (0.7-1.2)
    Enalapril1.0 (0.9-1.1)1.0 (0.8-1.1)4.9 (1.9-13)1.1 (1.0-1.3)
    Methyldopa1.7 (1.2-2.5)1.1 (0.4-2.9)0.4 (0.1-1.3)
    Simvastatin1.0 (1.0-1.1)0.8 (0.7-1.0)0.5 (0.1-2.1)1.2 (1.0-1.5)
    Sotalol1.0 (0.8-1.1)0.9 (0.7-1.3)2.2 (0.4-14)0.9 (0.7-1.2)
    Verapamil0.9 (0.9-1.0)1.0 (0.8-1.2)0.8 (0.2-4.2)1.1 (0.9-1.2)
Hypoglycaemics
    Metformin1.0 (0.9-1.2)1.3 (0.9-1.7)1.0 (0.1-8.2)0.8 (0.6-1.1)
    Tolbutamide0.8 (0.6-1.0)0.8 (0.5-1.5)1.0 (0.7-1.6)
Anticonvulsant
    Carbamazepine0.9 (0.8-1.1)0.7 (0.5-1.0)0.8 (0.1-10)0.8 (0.6-1.2)
    Valproate1.1 (0.9-1.4)0.9 (0.5-1.5)0.8 (0.5-1.4)
Cytotoxic medications
    Methotrexate1.3 (0.3-4.9)0.2 (0.01-14)
  • *Adjusted for age, period, sex, and education.