Table 1.

IRR of BCC, CMM, MCC, and SCC according to any use of specific photosensitizing medications for LT daily use

Medications for LT daily useBCCCMMMCCSCC
No. casesIRR (95% CI)*No. casesIRR (95% CI)*No. casesIRR (95% CI)*No. casesIRR (95% CI)*
Any use of LT medications30,8851.07 (1.05-1.08)6,2761.06 (1.02-1.10)901.58 (1.08-2.31)5,9121.16 (1.12-1.22)
Diuretic agents
    Bendroflumethiazide4441.0 (1.0-1.1)891.3 (1.0-1.6)10.7 (0.1-5.1)931.0 (0.8-1.2)
    Bumetanide4381.0 (0.9-1.1)610.9 (0.7-1.1)31.8 (0.6-5.8)1251.2 (1.0-1.4)
    Furosemide7,3391.0 (1.0-1.0)1,1291.0 (1.0-1.1)462.0 (1.3-2.8)2,4041.4 (1.3-1.4)
Nonsteroidal anti-inflammatory drugs
    Diclofenac9,9971.1 (1.1-1.1)2,1571.0 (1.0-1.1)271.5 (0.9-2.3)1,6461.1 (1.0-1.1)
    Ibuprofen17,3021.0 (1.0-1.1)3,8211.0 (1.0-1.1)431.2 (0.8-1.7)2,9391.0 (1.0-1.1)
    Indomethacin9911.0 (1.0-1.1)1791.0 (0.9-1.1)72.8 (1.3-5.9)2361.2 (1.1-1.4)
Cardiovascular medications
    Amiodarone2471.2 (1.0-1.3)381.2 (0.9-1.6)11.6 (0.2-11)611.2 (0.9-1.5)
    Atenolol1,5251.0 (1.0-1.1)2641.0 (0.9-1.1)71.8 (0.8-3.8)2851.0 (0.9-1.1)
    Captopril6571.0 (1.0-1.1)850.9 (0.7-1.1)42.0 (0.7-5.4)1751.2 (1.0-1.4)
    Enalapril2,8691.0 (1.0-1.0)5401.1 (1.0-1.2)81.0 (0.5-2.1)6641.1 (1.0-1.2)
    Methyldopa881.3 (1.0-1.6)201.5 (1.0-2.3)13.7 (0.5-27)201.3 (0.8-2.0)
    Simvastatin2,7421.0 (1.0-1.1)4861.0 (0.9-1.1)163.6 (2.0-6.4)5231.1 (1.0-1.2)
    Sotalol1,0841.2 (1.2-1.3)1611.2 (1.0-1.4)31.1 (0.4-3.6)2261.1 (1.0-1.3)
    Verapamil1,9801.2 (1.1-1.3)2751.1 (1.0-1.2)61.0 (0.5-2.4)4501.1 (1.0-1.3)
Hypoglycemics
    Metformin8250.8 (0.7-0.8)1700.9 (0.8-1.1)41.5 (0.6-4.2)2351.1 (1.0-1.3)
    Tolbutamide3110.9 (0.8-1.0)511.0 (0.8-1.3)10.8 (0.1-6.0)841.0 (0.8-1.3)
Anticonvulsants
    Carbamazepine7221.1 (1.0-1.2)1251.0 (0.9-1.2)31.7 (0.5-5.3)1681.3 (1.1-1.5)
    Valproate3791.3 (1.1-1.4)611.0 (0.8-1.3)11.2 (0.2-8.7)791.3 (1.1-1.6)
Cytotoxic medications
    Methotrexate171.9 (1.2-3.1)62.9 (1.3-6.5)021.7 (0.4-7.0)

Abbreviation: 95% CI, 95% confidence interval.

  • *Adjusted for age, period, sex, and education. The reference group is never users of the specific photosensitizing medication.