Table 5.

Association of the six single-nucleotide polymorphisms at 8q24 with prostate-specific antigen recurrence (Cox proportional hazard model adjusted by age at diagnosis, serum prostate-specific antigen at diagnosis, pathologic T stage, and Gleason grade)

Risk locusSNPRisk alleleGenotypenHR (95% CI)P
1Rs1447295A770.3066
CC1
CA0.528 (0.175-1.589)0.2556
AA0.191 (0.019-1.922)0.1599
2Rs6983561C780.6753
AA1
CA0.740 (0.240-2.281)0.6003
CC0.562 (0.157-2.012)0.3755
Rs13254738C750.8950
AA1
CA0.817 (0.243-2.746)0.7435
CC0.731 (0.197-2.718)0.6400
Broad11934905A77
GG1
AG1.813 (0.556-5.912)0.3242
3Rs6983267G75
GT1
GG0.562 (0.138-2.287)0.4213
Rs7000448T780.2916
CC1
TC0.713 (0.250-2.031)0.5268
TT0.375 (0.108-1.296)0.1210

Abbreviation: HR, hazard ratio.