Table 5.

Association of CASP10 V410I with breast and ovarian cancer risk

CASP10 V410IHR (95% CI)P*
Per-rare alleleHeterozygotesRare homozygotes
Breast cancer
    BRCA10.98 (0.84-1.15)0.94 (0.80-1.10)1.97 (1.04-3.72)0.129
    BRCA21.03 (0.80-1.31)1.06 (0.82-1.38)0.69 (0.21-2.25)0.738
Ovarian cancer
    BRCA11.12 (0.83-1.52)1.08 (0.78-1.52)1.86 (0.61-5.72)0.601
    BRCA21.78 (1.01-3.12)1.60 (0.85-2.98)10.23 (3.13-33.39)0.097
  • *Two–degree of freedom test.

  • Versus common homozygotes.