Table 3.

Genotype distributions for the CASP8 D302H and CASP10 V410I polymorphisms

CharacteristicCASP8 D302HCASP10 V410I
TotalGGCGCCTotalGGGAAA
BRCA14,8443,784983774,6944,08558623
    Breast cancer
        Not affected2,2411,725482342,2451,94628811
        Affected2,6032,059501432,4492,13929812
    Ovarian cancer
        Not affected4,2683,320876724,1223,58951320
        Affected5764641075572496733
BRCA22,5091,935535392,5332,18633314
    Breast cancer
        Not affected1,061834214131,1109571458
        Affected1,4481,101321261,4231,2291886
    Ovarian cancer
        Not affected2,3601,816506382,3812,06330810
        Affected149119291152123254