Table 2.

Molecular features of colon cancer according to CTSB expression

Molecular featureTotalCTSB (−)CTSB (+)P
No. (%)No. (%)No. (%)
MSI status0.84
    MSI-low/MSS319 (79)45 (78)274 (79)
    MSI-high87 (21)13 (22)74 (21)
CIMP status0.49
    CIMP-low/0326 (81)45 (78)281 (81)
    CIMP-high77 (19)12 (22)64 (19)
BRAF mutation0.43
    (−)340 (84)50 (88)290 (84)
    (+)64 (16)7 (12)57 (16)
KRAS mutation0.01
    (−)254 (63)44 (77)210 (60)
    (+)152 (37)13 (23)139 (40)
PIK3CA mutation0.76
    (−)300 (84)42 (86)258 (84)
    (+)56 (16)7 (14)49 (16)
LINE-1 methylation level (mean ± SD)60.4 ± 9.261.7 ± 9.460.2 ± 9.20.25
TP53 expression0.63
    (−)264 (65)40 (68)224 (65)
    (+)142 (35)19 (32)123 (35)
PTGS2 (COX-2) expression0.72
    (−)156 (38)21 (36)135 (39)
    (+)251 (62)37 (64)214 (61)

Abbreviation: MSS, microsatellite stable.