Table 1.

Clinical and pathologic features of colon cancer according to cathepsin B expression

Clinical or pathologic featureTotalCTSB (−)CTSB (+)P
No. (%)No (%)No (%)
All cases558101457
Gender0.02
    Male192 (34)25 (25)167 (37)
    Female366 (66)76 (75)290 (63)
Mean age ± SD, years67.2 ± 8.267.8 ± 8.867.1 ± 8.10.43
Body mass index (kg/m2)0.58
    <30459 (82)85 (84)374 (82)
    ≥3099 (18)16 (16)83 (18)
Family history of colorectal cancer in any first-degree relative0.27
    (−)418 (75)80 (79)338 (74)
    (+)140 (25)21 (21)119 (26)
Tumor location0.87
    Right344 (62)63 (62)281 (61)
    Left214 (38)38 (38)176 (39)
Stage0.19
    I108 (19)21 (21)87 (19)
    II194 (35)28 (28)166 (36)
    III150 (27)36 (36)114 (25)
    IV81 (15)12 (12)69 (15)
    Missing25 (4.5)4 (4.0)21 (4.6)
Tumor grade0.28
    Low500 (90)87 (87)413 (91)
    High56 (10)13 (13)43 (9.4)
Mucinous component0.54
    0%269 (52)45 (51)224 (53)
    >0%245 (48)46 (49)199 (47)
Signet ring cell component0.24
    0%428 (88)76 (84)352 (89)
    >0%58 (12)14 (16)44 (11)