Table 3.

Association between baseline plasma tHcy and number of adenomas at the baseline exam

Baseline homocysteine (μmol/L)Adjustor set A*Adjustor set B
OR (95% CI)OR (95% CI)
≤7.95ReferenceReference
7.96-9.261.15 (0.74-1.79)1.02 (0.63-1.66)
9.27-11.251.37 (0.87-2.16)1.17 (0.73-1.88)
>11.251.49 (0.95-2.31)1.18 (0.74-1.86)
P trend = 0.06P trend = 0.43
  • *Adjustor set A consists of age, sex, study center, alcohol (continuous), BMI (continuous), and current smoking.

  • Adjustor set B consists of age, sex, study center, alcohol (continuous), BMI (continuous), current smoking, plasma B2, plasma B6, plasma B12, and plasma folate.

  • OR calculated using a proportional odds model where the outcome is number of baseline adenomas (1, 2, 3, 4,or 5+).