Table 4.

Conditional logistic regression showing odds ratios and 95% confidence interval of cancer in situ and invasive squamous cell carcinoma among women with transient, acquired, or persistent HPV16 infection compared with those negative for HPV16 in both the first and second smears

Conditional analysis*CIS (ncases = 241; nctrls = 241)SCC (ncases = 155; nctrls = 155)
OR (95% CI)OR (95% CI)
HPV16 status in the first and second smear
Negative −/−1.00 (reference)*1.00 (reference)*
Transience +/−1.2 (0.5-3.1)2.6 (0.8-8.2)
Acquisition −/+7.6 (2.8-20.5)2.9 (1.2-7.3)
Persistence +/+18.5 (6.5-52.9)19.5 (4.7-81.7)
  • *Estimates were controlled for matching criteria (county, date of entry into cohort, and age at first normal smear).