Table 2.

Prevalence of specific HPV types and HPV type groupings in first and last Pap smear for cancer in situ and invasive squamous cell carcinoma cases and their matched controls

HPV typeCancer in situInvasive squamous cell carcinoma
High-risk (HR) or Low-risk (LR)First smearLast smearFirst smearLast smear
Cases (n = 515), No. (%)*Controls (n = 515), No. (%)*Cases (n = 515), No. (%)*Controls (n = 515), No. (%)*Cases (n = 315), No. (%)*Controls (n = 315), No. (%)*Cases (n = 315), No. (%)*Controls (n = 315), No. (%)*
Any HPVHR/LR301 (59)94 (18)407 (79)72 (14)191 (61)58 (18)224 (71)45 (14)
HPV-16/18HR179 (35)34 (7)262 (51)26 (5)140 (44)21 (7)158 (50)17 (5)
Non-16/18 HRHPVHR146 (28)54 (11)198 (39)35 (7)65 (21)35 (11)77 (24)20 (6)
Any HRHPVHR288 (56)82 (16)396 (78)57 (11)184 (58)49 (16)220 (70)33 (11)
Any LRHPVLR34 (7)19 (4)32 (6)16 (3)12 (4)13 (4)8 (3)12 (4)
Multiple HPV typesHR/LR57 (11)14 (3)82 (16)9 (2)28 (9)11 (4)19 (6)6 (2)
HPV-6LR7 (1)2 (0)4 (0)3 (1)1 (0)002 (1)
HPV-7LR001 (0)1 (0)0000
HPV-11LR5 (1)1 (0)4 (0)1 (0)01 (0)01 (0)
HPV-16HR158 (31)28 (5)235 (46)19 (4)118 (38)16 (5)131 (42)12 (4)
HPV-18HR30 (6)7 (1)36 (7)8 (2)27 (9)6 (2)29 (9)6 (2)
HPV-31HR34 (7)17 (3)49 (10)8 (2)13 (4)7 (2)16 (5)3 (1)
HPV-33HR34 (7)5 (1)41 (8)4 (1)16 (5)2 (1)16 (5)2 (1)
HPV-35HR11 (2)3 (1)14 (3)2 (0)2 (1)4 (1)3 (1)0
HPV-39HR5 (1)3 (1)7 (1)4 (1)4 (1)1 (0)5 (2)1 (0)
HPV-42LR16 (3)12 (2)20 (4)8 (2)7 (2)9 (3)6 (2)7 (2)
HPV-43LR3 (1)2 (0)1 (0)1 (0)1 (0)2 (1)1 (0)1 (0)
HPV-45HR16 (3)3 (1)24 (5)4 (1)15 (5)6 (2)25 (8)7 (2)
HPV-51HR8 (2)5 (1)14 (3)3 (1)3 (1)2 (1)1 (0)1 (0)
HPV-52HR18 (4)4 (1)24 (5)5 (1)3 (1)4 (1)4 (1)1 (0)
HPV-56HR14 (3)9 (2)19 (4)8 (2)5 (2)2 (1)9 (3)2 (1)
HPV-58HR10 (2)3 (1)15 (3)3 (1)1 (0)2 (1)1 (0)2 (1)
HPV-59HR26 (5)10 (2)33 (6)7 (1)15 (5)9 (3)13 (4)6 (2)
HPV-66HR10 (2)5 (1)13 (3)3 (1)5 (2)5 (2)3 (1)4 (1)
HPV-68HR1 (0)1 (0)2 (0)1 (0)1 (0)1 (0)2 (1)0
HPV-70LR4 (1)3 (1)2 (0)4 (1)3 (1)2 (1)1 (0)2 (1)
HPV-73HR01 (0)02 (0)1 (0)2 (1)01 (0)
HPV-82HR1 (0)03 (1)00000
  • *Addition of individual HPV types exceeds the number of women due to multiple HPV infections in some women. Therefore, the sum of percentages of positive HPV infections may exceed 100%.