Table 2.

κ Statistics for agreement of ER and PR status from different data sources by study site, tumor characteristics, and cases' demographic characteristics

ERPROverall ER/PR
No. of casesκ (95% CI)No. of casesκ (95% CI)No. of casesκ (95% CI)
Study site
    Detroit2860.68 (0.59-0.76)2610.64 (0.55-0.73)2570.56 (0.48-0.64)
    Los Angeles7620.70 (0.65-0.76)6650.58 (0.52-0.65)6620.55 (0.49-0.60)
    P*0.620.320.71
Calendar year of diagnosis
    19941430.54 (0.41-0.67)1370.39 (0.24-0.54)1360.35 (0.24-0.46)
    19951790.66 (0.55-0.77)1660.59 (0.47-0.71)1660.52 (0.42-0.62)
    19963250.78 (0.71-0.85)2680.65 (0.56-0.74)2650.62 (0.55-0.70)
    19973020.72 (0.64-0.80)2680.65 (0.56-0.74)2660.60 (0.53-0.68)
    1998990.66 (0.51-0.82)870.67 (0.51-0.83)860.56 (0.42-0.69)
    P*0.020.040.001
Tumor size (source, SEER), cm
    <24720.64 (0.57-0.72)4080.57 (0.49-0.66)4040.53 (0.46-0.60)
    2-4.94450.75 (0.69-0.81)3960.61 (0.54-0.69)3940.57 (0.51-0.63)
    ≥5880.57 (0.41-0.74)840.53 (0.36-0.70)830.45 (0.31-0.59)
    Diffuse141313
    Unknown292525
    P*0.030.620.26
Tumor stage (source, SEER)
    Localized disease6150.70 (0.65-0.76)5350.59 (0.52-0.66)5310.56 (0.50-0.61)
    Regional disease (extension to lymph nodes)4090.68 (0.60-0.75)3700.63 (0.55-0.71)3670.54 (0.48-0.61)
    Distant metastases230.82 (0.60-1.00)200.38 (−0.02 to 0.78)200.51 (0.25-0.76)
    Unknown111
    P*0.450.420.91
Age at diagnosis
    <402000.74 (0.65-0.83)1880.62 (0.51-0.73)1860.59 (0.50-0.68)
    40-441820.63 (0.53-0.74)1680.62 (0.50-0.74)1670.51 (0.42-0.61)
    45-491640.70 (0.59-0.81)1420.66 (0.54-0.79)1410.58 (0.48-0.69)
    50-541870.72 (0.61-0.83)1630.71 (0.60-0.82)1610.62 (0.52-0.72)
    55-591530.70 (0.58-0.82)1290.54 (0.40-0.69)1280.51 (0.39-0.63)
    60-641620.62 (0.48-0.76)1360.36 (0.20-0.53)1360.41 (0.29-0.53)
    P*0.600.020.10
Race
    White6140.66 (0.60-0.72)5440.60 (0.53-0.67)5420.53 (0.48-0.59)
    African American4340.73 (0.67-0.79)3820.59 (0.52-0.67)3770.56 (0.50-0.63)
    P*0.110.980.51
  • *P value from the κ homogeneity χ2 test of Fleiss.