Table 2.

Positive rate of Tf alone, IFOBT alone, and Tf + IFOBT in fecal samples from colorectal cancer patients, premalignant subjects, and low-risk subjects (n = 110)

DiseasesnIFOBTTfTf + IFOBT
+++
Colorectal cancer4030 (75%)10 (25%)32 (80%)*8 (20%)36 (90%)*4 (10%)
Premalignant subjects3616 (44%)20 (56%)26 (72%)*,10 (28%)28 (78%)*,8 (22%)
Low risk population§344 (12%)30 (88%)8 (24%)26 (76%)10 (29%)24 (71%)
  • *P < 0.01 comparing to low-risk population by χ2 test.

  • Includes 16 subjects with high-risk adenomas (villous adenoma, adenoma with moderate-severe dysplasia, multiple adenoma or adenoma ≥1 cm) and 20 subjects with ulcerative colitis.

  • P < 0.05 comparing to IFOBT alone by χ2 test.

  • §Includes 8 subjects with small single adenoma (<0.5 cm) and 26 healthy subjects.