Table 3.

HPV transcripts and viral loads correlated with anal histology

Normal or AIN1
AIN 2/3
P*Total n
nMedian (IQR)nMedian (IQR)
p16 Transcripts (log10 copies/105 cells)844.64 (4.21-5.10)454.53 (4.06-5.32)0.68129
No. of HPV types1383.5 (2-6)745 (3-7)0.0006212
HPV viral load (log10 copies/105 cells)
    HPV DNA 16464.73 (3.80-5.32)395.18 (4.69-6.13)0.00385
    HPV DNA 18185.37 (3.91-6.47)236.01 (5.16-7.04)0.0741
    HPV DNA 31134.08 (3.86-5.07)195.52 (4.82-5.90)0.0832
HPV E6 (log10 copies/105 cells)
    HPV RNA 16256.09 (5.43-7.06)276.19 (5.47-7.16)0.7752
    HPV RNA 1895.05 (3.30-6.11)156.22 (5.07-6.90)0.05424
    HPV RNA 3186.44 (5.35-6.74)146.45 (5.76-6.96)0.7622
  • * Wilcoxon rank sum.