Table 1.

Association between prostate cancer risk and SNPs at Xp11

CHRSNPBPAllelesRisk alleleBlock*JHH
CGEMS
Frequency
Allelic
PTypeFrequency
Allelic
PType
CaseControlsOR (95% CI)CasesControlsOR (95% CI)
Xrs97263551,000,724A/TA20.330.321.06 (0.85-1.32)0.61Genotyped0.330.281.25 (1.04-1.51)1.71 × 02Imputed
Xrs1109172751,034,123A/CA20.210.201.09 (0.84-1.41)0.50Genotyped0.230.191.30 (1.06-1.60)1.05 × 02Genotyped
Xrs132730151,043,093T/CT30.390.331.32 (1.07-1.64)1.13 × 02Genotyped0.400.341.33 (1.12-1.58)1.10 × 03Genotyped
Xrs598742151,059,526G/TG30.400.341.31 (1.06-1.62)1.38 × 02Genotyped0.410.341.33 (1.12-1.57)1.16 × 03Imputed
Xrs594557251,062,719A/GA30.400.331.32 (1.06-1.63)1.26 × 02Genotyped0.410.341.33 (1.12-1.57)1.23 × 03Genotyped
Xrs594561951,074,708C/TC30.400.341.31 (1.06-1.63)1.28 × 02Genotyped0.410.331.40 (1.18-1.66)1.11 × 04Genotyped
Xrs594564251,133,714A/GA40.020.021.08 (0.53-2.19)0.84Genotyped0.040.031.37 (0.85-2.22)0.20Genotyped
Xrs313130251,143,890C/TC40.230.211.14 (0.89-1.47)0.29Genotyped0.250.201.34 (1.10-1.64)3.33 × 03Imputed
Xrs594564551,145,627A/GA40.050.041.22 (0.73-2.05)0.44Genotyped0.040.031.39 (0.87-2.21)0.17Imputed
Xrs313130151,149,503G/AG40.040.031.34 (0.76-2.38)0.31Genotyped0.030.021.32 (0.76-2.26)0.32Imputed
Xrs154123851,176,671G/CG40.390.321.35 (1.09-1.67)6.99 × 03Genotyped0.400.331.37 (1.15-1.63)3.98 × 04Imputed
Xrs594565251,177,331A/GA40.270.290.92 (0.73-1.15)0.47Genotyped0.290.310.89 (0.74-1.06)0.19Genotyped
Xrs272199751,177,728A/CA40.030.021.33 (0.68-2.59)0.40Genotyped0.010.011.30 (0.52-3.24)0.58Imputed
Xrs272199851,184,563C/AC40.010.004.45 (0.58-33.96)0.11Genotyped0.010.011.35 (0.51-3.56)0.54Imputed
Xrs154124251,186,589G/AG40.200.201.04 (0.81-1.35)0.76Genotyped0.210.191.11 (0.91-1.37)0.31Genotyped
Xrs705703951,195,647G/AG40.360.301.34 (1.07-1.67)9.52 × 03Genotyped0.370.321.24 (1.05-1.48)1.41 × 02Imputed
Xrs1239344351,361,128G/TG40.190.181.09 (0.84-1.42)0.53Genotyped0.200.191.12 (0.91-1.38)0.30Imputed
Xrs595108151,396,816C/TC40.060.070.88 (0.58-1.32)0.53Genotyped0.080.100.80 (0.58-1.10)0.17Imputed
Xrs159567951,398,670G/AG40.150.101.60 (1.15-2.23)5.46 × 03Genotyped0.140.101.46 (1.12-1.88)4.22 × 03Imputed
Xrs1238531851,403,149A/GA40.030.030.97 (0.52-1.83)0.93GenotypedNANANANA
  • Abbreviations: CHR, chromosome; BP, 95% base pair CI, 95% confidence interval; NA, not applicable.

  • * Indicates which haplotype block the SNPs falls in.