Table 1.

Risk of breast cancer associated with the SMAD7 and CRAC1 SNPs

Locus/SNPGenotypeMAF controlsCases
Controls
OR (95% CI)P trend
n%n%
rs4939827TT0.46834527.824828.2Reference
18q21TC62850.744050.01.03 (0.84-1.26)
CC26621.519221.81.00 (0.78-1.28)
Allelic OR1.00 (0.88-1.13)0.997
rs12953717CC0.44537530.027731.2Reference
18q21CT63050.443148.61.08 (0.89-1.32)
TT24419.517920.21.01 (0.79-1.29)
Allelic OR1.01 (0.89-1.15)0.856
rs4464148TT0.31758048.841546.9Reference
18q21TC54644.037742.61.04 (0.86-1.24)
CC1149.29210.40.89 (0.66-1.20)
Allelic OR0.98 (0.85-1.12)0.718
rs4779584CC0.18582566.857566.2Reference
15q13TC36429.526730.70.95 (0.79-1.15)
TT463.7273.11.19 (0.73-1.93)
Allelic OR1.00 (0.85-1.17)0.995
rs10318CC0.18080866.758267.4Reference
15q13CT35929.625229.21.03 (0.85-1.24)
TT443.6293.41.09 (0.68-1.77)
Allelic OR1.03 (0.88-1.22)0.684