Table 4.

Colon cancer mortality in obese patients (compared with nonobese patients) in strata of p27 status

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  • NOTE: p27-altered tumors include tumors with cytoplasmic p27 localization and tumors with loss of p27 expression. The multivariate, stage-matched conditional Cox model included the BMI variable stratified by p27 status, age, year of diagnosis, sex, family history of colorectal cancer, tumor location, stage, grade, KRAS, BRAF, PIK3CA, p53, p21, cyclin D1, β-catenin, COX-2, FASN, LINE-1 methylation, MSI, and CIMP.