Table 4.

Haplotypes/diplotypes of p21 and the odds of chronic benzene poisoning

Haplotype/Diplotypes*Cases (%)Controls (%)OR (95% CI)χ2P
Haplotype
    CC224 (37.2)184 (31.5)
    AT235 (39.0)267 (45.7)
    AC131 (21.8)120 (20.6)
    CT12 (2.0)13 (2.2)
Diplotypes
    CC/CC60 (19.9)37 (12.7)1.00
    CC/AT75 (24.9)91 (31.2)0.51 (0.30-0.85)6.810.009
    CC/CT26 (8.6)15 (5.1)1.07 (0.50-2.28)0.300.863
    AT/AT39 (13.0)48 (16.4)0.50 (0.28-0.90)5.350.021
    AT/CT79 (26.3)79 (27.1)0.62 (0.37-1.03)3.410.065
    Other diplotypes22 (7.3)22 (7.5)0.62 (0.30-1.27)1.750.186
  • * The allele order is C98A and C70T from left to right.

  • Some data were missing due to inability to amplify DNA.

  • All subgroups with frequencies <5% were combined as one group.