Table 3.

Haplotypes/diplotypes of p53 and the odds of chronic benzene poisoning

Haplotype/Diplotypes*Cases (%)Controls (%)OR (95% CI)χ2P
Haplotype
    WCC233 (38.1)222 (37.6)1.00
    WGC345 (56.4)335 (56.8)0.98 (0.77-1.24)0.020.876
    MCA13 (2.1)16 (2.7)0.77 (0.36-1.65)0.440.505
    WCA14 (2.3)12 (2.0)1.11 (0.50-2.46)0.070.794
Diplotypes
    WCC/WCC45 (15.1)44 (15.2)1.00
    WCC/WGC132 (44.3)126 (43.5)1.02 (0.63-1.66)0.010.922
    WGC/WGC95 (31.9)92 (31.7)1.01 (0.61-1.67)0.000.970
    Other diplotypes26 (8.7)28 (9.6)0.91 (0.46-1.79)0.080.780
  • * The allele order is intron3, C119G, and IVS6+62 C>A from left to right.

  • Data missing due to failure in DNA amplification.

  • All subgroups with frequencies <5% were combined as one group.